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Roy, Amit
- A Phytopharmacological Review on Lawsonia inermis L.
Authors
1 Columbia Institute of Pharmacy, Tekari, Raipur, C.G., IN
2 Columbia Institute of Pharmacy, Tekari, Raipur C.G, IN
Source
Research Journal of Science and Technology, Vol 4, No 3 (2012), Pagination: 93-107Abstract
Medicinal plants have very important place as they not only maintain the health and vitality of human beings and animals. India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The plant Lawsonia inermis L. (family- Lythraceae) commonly known as Henna or Mehndi is known for its cosmetic properties. This plant has relabeled that use of wildlife medicinal resources in the concern not only from conservation point of view but in the therapeutic point of view. Henna plant is a much branched glabrous shrub or small tree, cultivated for its leaves although stem bark, ischolar_mains, flowers and seeds have also been used in traditional medicine. The plant has been reported the various in-vitro and in-vivo studies to have antifungal, antibacterial, antiviral, antimicrobial, immunostimulant, wound healing, analgesic, hepatoprotective, antiinflammatory, antiparasitic, antitrypanosomal, antioxidant, antifertility, tuberculostatic, anticancer, enzyme inhibitory, memory and behaviour effectiveness, antitrypanosomal, antisickling, antidiabetic, and many other properties. Henna, the potential medicinal plant is the unique source of various pharmacologically important compounds. This review gives a bird’s eye view mainly on the pharmacognostic characteristics, traditional uses, phytochemistry and pharmacological actions of the plant.Keywords
Lawsonia inermis L., Traditional Medicine, Antiinflammatory, Enzyme Inhibitory, Phytochemistry, Pharmacological Actions.
- Screening of Antipyretic and Analgesic Potential of Ethanol Extract of Cassytha filiformis Leaves
Authors
1 Columbia Institute of Pharmacy, Tekari, Raipur (C.G.)-493111, IN
2 Oriental College of Pharmacy, Raisen Road, Bhopal-462021 (M.P.),, IN
3 Shridhar University, Pilani-333031 (Rajasthan), IN
4 Institute of Pharmacy, Kathog-177101 (H.P.), IN
Source
Research Journal of Science and Technology, Vol 4, No 3 (2012), Pagination: 129-131Abstract
The present study was undertaken to evaluate the antipyretic and analgesic activities of the alcohol extract of Cassytha filiformis leaves. The antipyretic activity of C. filiformis (25mg/kg, 50mg/kg and 100mg/kg) was studied in Brewer’s yeast induced pyrexia in rats. The analgesic activity of C. filiformis (25mg/kg, 50mg/kg and 100mg/kg) was studied using Eddy’s hot plate method and heat conduction method in mice. The extract showed significant reduction in the elevated body temperature of rat which was compared with standard Paracetamol. The extract produced significant increase in the reaction time by Eddy”s hot plate method and tail flick method in mice which was compared with standard diclofenac sodium. The alcohol extract of leaves of C. filiformis may have antipyretic and analgesic activities.Keywords
Cassytha filiformis, Antipyretic, Pyrexia, Analgesic, Paracetamo.- Antimutagenic Effects of Tribulus terristris Fruit Extract on Micronucleus
Authors
1 Columbia Institute of Pharmacy, Tekari, Raipur (C.G.)-493111, IN
2 Jawaharlal Nehru Cancer Hospital and Research Centre, Idgah Hills, Bhopal (MP), IN
Source
Research Journal of Science and Technology, Vol 4, No 3 (2012), Pagination: 140-142Abstract
In this study, the protective effect of hydromethanolic fruit extract of Tribulus terristris is reported against Cyclophosphamide (CP) induced micronuclei (MN) formation in bone marrow cells of mice. Swiss albino mice were treated with a single i.p. dose of 500, 1000 and 1500 mg/kg b.w. with Tribulus terristris fruit extract prior to CP administration. A significant inhibition was noticed in the micronuclei frequencies, as it gradually decreased with increase in concentration of the extract suggesting a protective effect and the extract alone had not induced MN formation, reiterating the fact that the extract has no pro-mutagenic components.Keywords
Micronucleus, Mutagenic, Tribulusterristris, Hydromethanolic.- Assessment of Bioactivity of an Ethnomedicine:Hyptis suaveolens (L.) Poit
Authors
1 Columbia Institute of Pharmacy, Pharmacy, Tekari, Raipur (C.G.), IN
Source
Research Journal of Science and Technology, Vol 4, No 1 (2012), Pagination: 1-5Abstract
The work reported in this study is a part of research project that encompasses pharmacological and phytochemical investigation of some ethnopharmacologically important plants of Chhattisgarh- India. Here preliminary work done on Hyptis suaveolens (L.) Poit. (H. suaveolens), is reported as this plant is being used to treat a wide assortment of diseases by the local inhabitants of Chhattisgarh. The pharmacological potential of this plant was evaluated by using some benchtop bioassay methods like antimicrobial, antioxidant, brine shrimp lethality test (BSLT) and crown gall tumor assay. These studies were carried out to screen H. suaveolens for its bioactivity so that further study can be carried out.
The alcoholic extract of H. suaveolens was fractioned into chloroform soluble and insoluble fraction and both were subjected for these in vitro studies. Both the fractions of H. suaveolens methanolic extract were found to exhibit significant activity in all the bioassay models. The results were compared with those produced by standards used in each study model respectively. The present study supports that the bioassay methods are simple reliable and convenient method for assessment of bioactivity of medicinal plants and lends support for their use in traditional medicine.